Issue · Apr 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any emailIssue · Apr 2026New this week: evidence-first longevity readsThe newsletter — one essay, Sunday morningsArchive access — every article, free to readPodcast coming soon — NotebookLM sessionsLetters from readers — reply to any email
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Recommendations for the week ahead

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The long read

A slower piece, on one thing.

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Rapamycin Side Effects and Safety: What Bryan Johnson's Experience Tells Us
Aging · In-depth essay

Rapamycin Side Effects and Safety: What Bryan Johnson's Experience Tells Us

A research-backed guide to rapamycin's side effects at anti-aging doses, from blood glucose changes to immune impacts, plus what Bryan Johnson's five-year experiment revealed.

Begin reading14 min readBy Jessica Lewis (JessieLew)
Letter from the editorial team

On the quiet parts of getting well.

Research shows weighted vest walking burns more calories proportional to load and may help maintain bone density -- but only during structured exercise, not passive wear.

The goal isn’t to be comfortable with change — it’s to be comfortable with one small change, on a schedule, held for a year.

From “Weighted Vest Walking and Hiking: Calorie Burn, Bone Density, and Beginner Guide” · The HL Benefits Editorial Team · Apr 2026
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The Quiet Podcast · Coming soon

Notebook-LM reads the magazine — deep-dive conversations, weekly.

We’re recording with NotebookLM. Expect a deep-dive and a short-form version of each issue’s best essays, delivered to your favorite podcast app when we launch.

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The daily read · Free

One essay, every morning. No theatre.

A short email with the day’s best piece, a quote we’re sitting with, and links we actually read. No upsell, no course. Unsubscribe in one click.

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